Gene information
Official symbol IL4
Official full name interleukin 4
Gene type protein-coding gene
Chromosome5q31.1
Alias symbolBSF1; IL-4; BCGF1; BCGF-1; MGC79402
Gene familyInterleukins
Resources
Entrez Gene 3565
HGNC HGNC:6014
Ensembl ENSG00000113520
Vega OTTHUMG00000059724
UCSC uc003kxk.3
GO terms: 261 records
GO Description Category LogP Number of genes Detail
GO:0000018 regulation of DNA recombination GO Biological Processes -2.30127410 6 More
GO:0001774 microglial cell activation GO Biological Processes -13.1367436 11 More
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0002227 innate immune response in mucosa GO Biological Processes -2.28850890 3 More
GO:0002252 immune effector process GO Biological Processes -24.2648770 43 More
GO:0002263 cell activation involved in immune response GO Biological Processes -10.3401505 18 More
GO:0002269 leukocyte activation involved in inflammatory response GO Biological Processes -12.6026553 11 More
GO:0002274 myeloid leukocyte activation GO Biological Processes -20.6988408 25 More
GO:0002285 lymphocyte activation involved in immune response GO Biological Processes -7.04246662 12 More
GO:0002286 T cell activation involved in immune response GO Biological Processes -5.33688125 8 More
GO:0002287 alpha-beta T cell activation involved in immune response GO Biological Processes -5.32260704 6 More
GO:0002292 T cell differentiation involved in immune response GO Biological Processes -5.02945267 6 More
GO:0002293 alpha-beta T cell differentiation involved in immune response GO Biological Processes -5.32260704 6 More
GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response GO Biological Processes -5.40213264 6 More
GO:0002366 leukocyte activation involved in immune response GO Biological Processes -10.4998832 18 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0002521 leukocyte differentiation GO Biological Processes -12.4650129 27 More
GO:0002573 myeloid leukocyte differentiation GO Biological Processes -7.83519790 12 More
GO:0002637 regulation of immunoglobulin production GO Biological Processes -8.47662495 11 More
GO:0002639 positive regulation of immunoglobulin production GO Biological Processes -6.83160707 8 More
GO:0002673 regulation of acute inflammatory response GO Biological Processes -15.6954767 14 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0002685 regulation of leukocyte migration GO Biological Processes -36.943236 43 More
GO:0002687 positive regulation of leukocyte migration GO Biological Processes -31.0737422 33 More
GO:0002688 regulation of leukocyte chemotaxis GO Biological Processes -31.6279962 32 More
GO:0002690 positive regulation of leukocyte chemotaxis GO Biological Processes -28.1480961 27 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002695 negative regulation of leukocyte activation GO Biological Processes -9.84552767 31 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002698 negative regulation of immune effector process GO Biological Processes -11.7829906 16 More
GO:0002699 positive regulation of immune effector process GO Biological Processes -18.3926498 29 More
GO:0002700 regulation of production of molecular mediator of immune response GO Biological Processes -19.7615296 26 More
GO:0002702 positive regulation of production of molecular mediator of immune response GO Biological Processes -12.4206918 17 More
GO:0002703 regulation of leukocyte mediated immunity GO Biological Processes -18.0432682 27 More
GO:0002705 positive regulation of leukocyte mediated immunity GO Biological Processes -8.38274670 14 More
GO:0002706 regulation of lymphocyte mediated immunity GO Biological Processes -13.7265777 21 More
GO:0002708 positive regulation of lymphocyte mediated immunity GO Biological Processes -8.31079168 13 More
GO:0002709 regulation of T cell mediated immunity GO Biological Processes -8.74858930 12 More
GO:0002711 positive regulation of T cell mediated immunity GO Biological Processes -6.00483593 8 More
GO:0002712 regulation of B cell mediated immunity GO Biological Processes -6.15575915 8 More
GO:0002714 positive regulation of B cell mediated immunity GO Biological Processes -6.30679788 7 More
GO:0002718 regulation of cytokine production involved in immune response GO Biological Processes -15.9157324 18 More
GO:0002720 positive regulation of cytokine production involved in immune response GO Biological Processes -8.11676834 10 More
GO:0002724 regulation of T cell cytokine production GO Biological Processes -9.29772341 9 More
GO:0002726 positive regulation of T cell cytokine production GO Biological Processes -6.29956701 6 More
GO:0002761 regulation of myeloid leukocyte differentiation GO Biological Processes -12.4818724 17 More
GO:0002819 regulation of adaptive immune response GO Biological Processes -16.0189388 24 More
GO:0002820 negative regulation of adaptive immune response GO Biological Processes -3.17098953 5 More
GO:0002821 positive regulation of adaptive immune response GO Biological Processes -12.1298033 16 More
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -14.6775052 22 More
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -3.34951384 5 More
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO Biological Processes -10.1498702 14 More
GO:0002828 regulation of type 2 immune response GO Biological Processes -8.52846045 8 More
GO:0002831 regulation of response to biotic stimulus GO Biological Processes -10.931136 25 More
GO:0002886 regulation of myeloid leukocyte mediated immunity GO Biological Processes -10.0272645 11 More
GO:0002889 regulation of immunoglobulin mediated immune response GO Biological Processes -6.15575915 8 More
GO:0002891 positive regulation of immunoglobulin mediated immune response GO Biological Processes -6.30679788 7 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0005126 cytokine receptor binding GO Molecular Functions -41.4908940 50 More
GO:0006066 alcohol metabolic process GO Biological Processes -16.7128396 29 More
GO:0006140 regulation of nucleotide metabolic process GO Biological Processes -7.41911571 18 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0007162 negative regulation of cell adhesion GO Biological Processes -21.5212108 58 More
GO:0008083 growth factor activity GO Molecular Functions -26.3260872 31 More
GO:0008202 steroid metabolic process GO Biological Processes -19.3229835 29 More
GO:0008203 cholesterol metabolic process GO Biological Processes -19.4799126 22 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010506 regulation of autophagy GO Biological Processes -5.54010569 34 More
GO:0010508 positive regulation of autophagy GO Biological Processes -4.14985165 17 More
GO:0010632 regulation of epithelial cell migration GO Biological Processes -42.8870194 81 More
GO:0016125 sterol metabolic process GO Biological Processes -19.5624674 23 More
GO:0016239 positive regulation of macroautophagy GO Biological Processes -4.30642477 12 More
GO:0016241 regulation of macroautophagy GO Biological Processes -3.91265693 18 More
GO:0017157 regulation of exocytosis GO Biological Processes -7.48561663 15 More
GO:0018108 peptidyl-tyrosine phosphorylation GO Biological Processes -3.43405510 8 More
GO:0018212 peptidyl-tyrosine modification GO Biological Processes -3.37492500 8 More
GO:0022407 regulation of cell-cell adhesion GO Biological Processes -32.4337382 53 More
GO:0022408 negative regulation of cell-cell adhesion GO Biological Processes -15.9068791 40 More
GO:0022409 positive regulation of cell-cell adhesion GO Biological Processes -25.7751074 39 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030098 lymphocyte differentiation GO Biological Processes -7.22308617 17 More
GO:0030099 myeloid cell differentiation GO Biological Processes -6.71806250 15 More
GO:0030100 regulation of endocytosis GO Biological Processes -14.0757782 22 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030183 B cell differentiation GO Biological Processes -4.52538214 9 More
GO:0030217 T cell differentiation GO Biological Processes -5.22709721 11 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0030888 regulation of B cell proliferation GO Biological Processes -7.97568198 10 More
GO:0030890 positive regulation of B cell proliferation GO Biological Processes -8.50618951 9 More
GO:0031331 positive regulation of cellular catabolic process GO Biological Processes -13.5134767 30 More
GO:0031341 regulation of cell killing GO Biological Processes -10.2641102 14 More
GO:0031342 negative regulation of cell killing GO Biological Processes -3.33685104 4 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032147 activation of protein kinase activity GO Biological Processes -11.6086663 28 More
GO:0032653 regulation of interleukin-10 production GO Biological Processes -10.1959901 18 More
GO:0032656 regulation of interleukin-13 production GO Biological Processes -4.09160195 4 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0032720 negative regulation of tumor necrosis factor production GO Biological Processes -18.6356508 28 More
GO:0032733 positive regulation of interleukin-10 production GO Biological Processes -8.60591296 9 More
GO:0032736 positive regulation of interleukin-13 production GO Biological Processes -4.89406977 4 More
GO:0032944 regulation of mononuclear cell proliferation GO Biological Processes -24.6915018 34 More
GO:0032946 positive regulation of mononuclear cell proliferation GO Biological Processes -20.2231223 25 More
GO:0033003 regulation of mast cell activation GO Biological Processes -4.83325597 6 More
GO:0033006 regulation of mast cell activation involved in immune response GO Biological Processes -5.56777868 6 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0035710 CD4-positive, alpha-beta T cell activation GO Biological Processes -4.53716649 6 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042093 T-helper cell differentiation GO Biological Processes -5.40213264 6 More
GO:0042102 positive regulation of T cell proliferation GO Biological Processes -13.4787271 17 More
GO:0042110 T cell activation GO Biological Processes -7.78997285 18 More
GO:0042113 B cell activation GO Biological Processes -5.56585733 12 More
GO:0042116 macrophage activation GO Biological Processes -15.3664951 15 More
GO:0042129 regulation of T cell proliferation GO Biological Processes -18.0871480 25 More
GO:0042509 regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.4049069 20 More
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.8380655 19 More
GO:0043030 regulation of macrophage activation GO Biological Processes -14.6396218 15 More
GO:0043300 regulation of leukocyte degranulation GO Biological Processes -5.75997337 7 More
GO:0043304 regulation of mast cell degranulation GO Biological Processes -5.73056952 6 More
GO:0043367 CD4-positive, alpha-beta T cell differentiation GO Biological Processes -4.83197184 6 More
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation GO Biological Processes -5.90313372 12 More
GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation GO Biological Processes -2.82210951 5 More
GO:0043457 regulation of cellular respiration GO Biological Processes -4.43542328 10 More
GO:0043467 regulation of generation of precursor metabolites and energy GO Biological Processes -10.8295915 27 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0045191 regulation of isotype switching GO Biological Processes -4.08159325 5 More
GO:0045321 leukocyte activation GO Biological Processes -25.4958219 48 More
GO:0045346 regulation of MHC class II biosynthetic process GO Biological Processes -9.43730348 7 More
GO:0045348 positive regulation of MHC class II biosynthetic process GO Biological Processes -9.26986898 6 More
GO:0045580 regulation of T cell differentiation GO Biological Processes -7.18541630 25 More
GO:0045581 negative regulation of T cell differentiation GO Biological Processes -3.22341771 8 More
GO:0045582 positive regulation of T cell differentiation GO Biological Processes -5.99210992 10 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045619 regulation of lymphocyte differentiation GO Biological Processes -8.78322888 17 More
GO:0045620 negative regulation of lymphocyte differentiation GO Biological Processes -5.62617381 12 More
GO:0045621 positive regulation of lymphocyte differentiation GO Biological Processes -6.96534841 12 More
GO:0045622 regulation of T-helper cell differentiation GO Biological Processes -5.35296451 10 More
GO:0045637 regulation of myeloid cell differentiation GO Biological Processes -9.39364926 18 More
GO:0045670 regulation of osteoclast differentiation GO Biological Processes -10.2566667 12 More
GO:0045671 negative regulation of osteoclast differentiation GO Biological Processes -3.32372992 4 More
GO:0045785 positive regulation of cell adhesion GO Biological Processes -29.6368249 50 More
GO:0045807 positive regulation of endocytosis GO Biological Processes -11.0143833 14 More
GO:0045830 positive regulation of isotype switching GO Biological Processes -3.49817224 4 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0045911 positive regulation of DNA recombination GO Biological Processes -1.99479187 4 More
GO:0045921 positive regulation of exocytosis GO Biological Processes -5.75584660 9 More
GO:0045981 positive regulation of nucleotide metabolic process GO Biological Processes -9.35726225 15 More
GO:0046425 regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.5317026 20 More
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.8890337 15 More
GO:0046631 alpha-beta T cell activation GO Biological Processes -4.13140497 7 More
GO:0046632 alpha-beta T cell differentiation GO Biological Processes -3.95887136 6 More
GO:0046634 regulation of alpha-beta T cell activation GO Biological Processes -7.20313216 11 More
GO:0046636 negative regulation of alpha-beta T cell activation GO Biological Processes -2.81707928 4 More
GO:0046637 regulation of alpha-beta T cell differentiation GO Biological Processes -6.05306731 14 More
GO:0046649 lymphocyte activation GO Biological Processes -10.1732143 26 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048259 regulation of receptor-mediated endocytosis GO Biological Processes -11.3903749 15 More
GO:0048260 positive regulation of receptor-mediated endocytosis GO Biological Processes -10.1090317 11 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0050670 regulation of lymphocyte proliferation GO Biological Processes -22.6006415 32 More
GO:0050671 positive regulation of lymphocyte proliferation GO Biological Processes -19.1485102 24 More
GO:0050688 regulation of defense response to virus GO Biological Processes -1.79095362 4 More
GO:0050691 regulation of defense response to virus by host GO Biological Processes -2.66162124 4 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.9747849 34 More
GO:0050777 negative regulation of immune response GO Biological Processes -11.1440698 32 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
GO:0050863 regulation of T cell activation GO Biological Processes -20.3209154 36 More
GO:0050864 regulation of B cell activation GO Biological Processes -7.98662389 16 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050866 negative regulation of cell activation GO Biological Processes -13.9027363 39 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0050868 negative regulation of T cell activation GO Biological Processes -5.59075646 10 More
GO:0050870 positive regulation of T cell activation GO Biological Processes -17.6497748 28 More
GO:0050871 positive regulation of B cell activation GO Biological Processes -8.77049404 15 More
GO:0050920 regulation of chemotaxis GO Biological Processes -36.3269885 43 More
GO:0050921 positive regulation of chemotaxis GO Biological Processes -35.4880405 36 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051052 regulation of DNA metabolic process GO Biological Processes -4.01973325 42 More
GO:0051054 positive regulation of DNA metabolic process GO Biological Processes -3.76901955 13 More
GO:0051249 regulation of lymphocyte activation GO Biological Processes -22.6120519 46 More
GO:0051250 negative regulation of lymphocyte activation GO Biological Processes -7.76846228 25 More
GO:0051251 positive regulation of lymphocyte activation GO Biological Processes -20.2181987 37 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0061900 glial cell activation GO Biological Processes -13.6981492 12 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0062013 positive regulation of small molecule metabolic process GO Biological Processes -17.9792910 37 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070665 positive regulation of leukocyte proliferation GO Biological Processes -21.5362473 27 More
GO:0070851 growth factor receptor binding GO Molecular Functions -16.9609899 22 More
GO:0071622 regulation of granulocyte chemotaxis GO Biological Processes -10.3031127 11 More
GO:0071624 positive regulation of granulocyte chemotaxis GO Biological Processes -4.01585848 7 More
GO:0071675 regulation of mononuclear cell migration GO Biological Processes -19.9332328 23 More
GO:0071677 positive regulation of mononuclear cell migration GO Biological Processes -15.5919825 16 More
GO:0090287 regulation of cellular response to growth factor stimulus GO Biological Processes -21.1381780 60 More
GO:0090288 negative regulation of cellular response to growth factor stimulus GO Biological Processes -9.39414218 23 More
GO:0097028 dendritic cell differentiation GO Biological Processes -1.97210978 3 More
GO:0097190 apoptotic signaling pathway GO Biological Processes -11.7839485 23 More
GO:0097191 extrinsic apoptotic signaling pathway GO Biological Processes -9.74858067 13 More
GO:0120161 regulation of cold-induced thermogenesis GO Biological Processes -19.1025541 38 More
GO:0120162 positive regulation of cold-induced thermogenesis GO Biological Processes -19.5569802 32 More
GO:0150076 neuroinflammatory response GO Biological Processes -13.2187099 12 More
GO:0150077 regulation of neuroinflammatory response GO Biological Processes -14.4671881 13 More
GO:0150079 negative regulation of neuroinflammatory response GO Biological Processes -5.31723275 7 More
GO:1900221 regulation of amyloid-beta clearance GO Biological Processes -7.04725442 6 More
GO:1900223 positive regulation of amyloid-beta clearance GO Biological Processes -4.05291246 3 More
GO:1900542 regulation of purine nucleotide metabolic process GO Biological Processes -7.57719972 18 More
GO:1900544 positive regulation of purine nucleotide metabolic process GO Biological Processes -9.35726225 15 More
GO:1901615 organic hydroxy compound metabolic process GO Biological Processes -22.7091625 41 More
GO:1901857 positive regulation of cellular respiration GO Biological Processes -4.58476241 4 More
GO:1902105 regulation of leukocyte differentiation GO Biological Processes -18.8286876 32 More
GO:1902106 negative regulation of leukocyte differentiation GO Biological Processes -7.27922558 19 More
GO:1902107 positive regulation of leukocyte differentiation GO Biological Processes -14.6775052 22 More
GO:1902652 secondary alcohol metabolic process GO Biological Processes -19.9585075 23 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
GO:1903038 negative regulation of leukocyte cell-cell adhesion GO Biological Processes -10.2281373 27 More
GO:1903039 positive regulation of leukocyte cell-cell adhesion GO Biological Processes -20.7355312 32 More
GO:1903131 mononuclear cell differentiation GO Biological Processes -9.35861236 21 More
GO:1903305 regulation of regulated secretory pathway GO Biological Processes -6.01402466 11 More
GO:1903307 positive regulation of regulated secretory pathway GO Biological Processes -2.97443173 8 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -18.2876323 28 More
GO:1903578 regulation of ATP metabolic process GO Biological Processes -8.20286273 19 More
GO:1903580 positive regulation of ATP metabolic process GO Biological Processes -9.55155535 14 More
GO:1903659 regulation of complement-dependent cytotoxicity GO Biological Processes -4.05291246 3 More
GO:1903706 regulation of hemopoiesis GO Biological Processes -16.2759166 33 More
GO:1903707 negative regulation of hemopoiesis GO Biological Processes -7.72888419 20 More
GO:1903708 positive regulation of hemopoiesis GO Biological Processes -14.6775052 22 More
GO:1903844 regulation of cellular response to transforming growth factor beta stimulus GO Biological Processes -8.41113232 25 More
GO:1904035 regulation of epithelial cell apoptotic process GO Biological Processes -21.2824424 33 More
GO:1904036 negative regulation of epithelial cell apoptotic process GO Biological Processes -12.0631217 12 More
GO:1904892 regulation of receptor signaling pathway via STAT GO Biological Processes -12.9980471 24 More
GO:1904894 positive regulation of receptor signaling pathway via STAT GO Biological Processes -11.2917234 16 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000351 regulation of endothelial cell apoptotic process GO Biological Processes -18.6276983 25 More
GO:2000352 negative regulation of endothelial cell apoptotic process GO Biological Processes -10.8868003 10 More
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation GO Biological Processes -5.84288222 8 More
GO:2000551 regulation of T-helper 2 cell cytokine production GO Biological Processes -4.89406977 4 More
GO:2001233 regulation of apoptotic signaling pathway GO Biological Processes -35.8481080 51 More
GO:2001234 negative regulation of apoptotic signaling pathway GO Biological Processes -32.1748782 40 More
GO:2001236 regulation of extrinsic apoptotic signaling pathway GO Biological Processes -20.7647111 26 More
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway GO Biological Processes -19.1764933 21 More
KEGG pathways: 16 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04630 JAK-STAT signaling pathway KEGG Pathway -14.4088859 21 More
hsa04640 Hematopoietic cell lineage KEGG Pathway -11.4657972 15 More
hsa04657 IL-17 signaling pathway KEGG Pathway -16.8039621 19 More
hsa04658 Th1 and Th2 cell differentiation KEGG Pathway -5.18694144 15 More
hsa04659 Th17 cell differentiation KEGG Pathway -9.80516906 14 More
hsa04660 T cell receptor signaling pathway KEGG Pathway -4.46130434 8 More
hsa04664 Fc epsilon RI signaling pathway KEGG Pathway -4.79120438 7 More
hsa04672 Intestinal immune network for IgA production KEGG Pathway -7.87779205 9 More
hsa05140 Leishmaniasis KEGG Pathway -12.4439861 14 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05310 Asthma KEGG Pathway -7.19451595 7 More
hsa05320 Autoimmune thyroid disease KEGG Pathway -5.52369866 7 More
hsa05321 Inflammatory bowel disease KEGG Pathway -16.3800424 16 More
hsa05330 Allograft rejection KEGG Pathway -10.3501019 10 More
Drug-Gene interaction
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Related drugs: 4 records
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
interleukin-4 proteomics good predictor left ventricular dysfunction[prognosis (bad)] acute ST elevation myocardial infarction Szkodzinski J et al. Heart Vessels. 2011
NM_000589.4:c.-589C>T genomics myocardial infarction[diagnosis] myocardial infarction Paffen E et al. J Thromb Haemost. 2008
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